Daily Vacuuming of Mattresses Significantly Reduces Dust Mite Allergens, Bacterial Endotoxin, and Fungal Beta-glucan

Wu FF, Wu MW, Pierse N, Crane J, Siebers R

Abstract


BACKGROUND AND AIMS: Atopic patients are advised to cover their mattresses with occlusive coverings; however, these are not cheap. We investigated whether daily vacuum cleaning of mattresses significantly reduces content of house dust mite allergens, bacterial endotoxin, and fungal beta-glucan.

 

METHODS: Twenty volunteers vacuumed their mattress daily for 8 weeks. Dust samples collected at two weekly intervals were analyzed for house dust mite allergens (Der p 1 and Der f 1) by double monoclonal antibody ELISA and for endotoxin and beta-glucan by the Limulus amoebocyte lysate kinetic assay. Results are presented as geometric means with 95% confidence interval (CI).

 

RESULTS: Total house dust mite allergens (Der p 1 + Der f 1) significantly reduced from a geometric mean (95% CI) of 4.07 μg (2.44-6.79) at the start to 0.42 μg (0.21-0.81) at week 8. Total endotoxin and beta-glucan were also significantly reduced from 13.6 EU (8.6-21.4) to 3.4 EU (2.3-5.0) and from 94.4 μg (57.1-156.2) to 19.7 μg (10.2-37.9), respectively (p for trend >.0001). Percentage reductions in total house dust mite allergens, endotoxin, and beta-glucan after 8 weeks of daily vacuum cleaning were 85.1% (80.1-90.1), 71.0% (70.4-81.0), and 75.7% (70.4-81.0), respectively. This was mainly due to a 77.7% (70.8-84.7) reduction in total dust.

 

CONCLUSION: Daily vacuum cleaning of mattresses over time significantly reduces house dust mite allergens, endotoxin, and beta-glucan. This gives atopic patients a practical and cheaper alternative to reduce their exposure to indoor house dust mite allergens and microbial bio-contaminants.
 
PMID: 22316179


ORIGINAL ARTICLE 

 

J Asthma. 2012 Mar; vol. 49(2) pp. 139-43
 
Authors
Wu FF, Wu MW, Pierse N, Crane J, Siebers R

 

Authors' Affiliation
International Emergency Medical Development Center, Show Chwan Memorial Hospital, Changhua City, Taiwan

 

Daily Vacuuming of Mattresses Significantly Reduces Dust Mite Allergens, Bacterial Endotoxin, and Fungal Beta-glucan:  Created on March 28th, 2012.  Last Modified on March 28th, 2012

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