Effectiveness of a Novel Ozone-based System for the Rapid High-level Disinfection of Health Care Spaces and Surfaces

Zoutman, Shannon, Mandel

Abstract

Vapor-based fumigant systems for disinfection of health care surfaces and spaces is an evolving technology. A new system (AsepticSure) uses an ozone-based process to create a highly reactive oxidative vapor with broad and high-level antimicrobial properties.

Methods

Ozone gas at 50-500 ppm was combined with 3% hydrogen peroxide vapor in a test chamber and upscaled in rooms measuring 82 m3 and 90 m3 in area. Test organisms included methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococcus, Escherichia coli, Pseudomonas aeruginosa, Clostridium difficile, and Bacillus subtilis spores dried onto steel discs or cotton gauze pads.

Results

The combination of 80-ppm ozone with 1% hydrogen peroxide vapor achieved a very high level of disinfection, with a ≥6 log10 reduction in the bacteria and spores tested on steel discs and MRSA tested on cotton gauze during a 30- to 90-minute exposure. The entire system was scalable such that it achieved the same high level of disinfection in both the 81-m3 and 90-m3 rooms in 60-90 minutes.

Conclusion

The ozone hydrogen peroxide vapor system provides a very high level of disinfection of steel and gauze surfaces against health care-associated bacterial pathogens. The system is an advanced oxidative process providing a rapid and effective means of disinfecting health care surfaces and spaces.

Authors 

Dick Zoutman, MD
Michael Shannon, MD, MSc
Arkady Mandel, MD, PhD, DSc

Published online 06 May 2011.

 

Conflict of interest: Research funded by Medizone International Inc.

PII: S0196-6553(11)00160-X

doi:10.1016/j.ajic.2011.01.012

© 2011 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc All rights reserved.

 

ORIGINAL ARTICLE

 

Effectiveness of a Novel Ozone-based System for the Rapid High-level Disinfection of Health Care Spaces and Surfaces:  Created on December 22nd, 2011.  Last Modified on December 22nd, 2011

2 Comments

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Allen Rathey · 7 years ago

We have added the following info:

Published online 06 May 2011.

Conflict of interest: Research funded by Medizone International Inc.

PII: S0196-6553(11)00160-X

doi:10.1016/j.ajic.2011.01.012

© 2011 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc All rights reserved.

December 22nd, 2011 | 2:59pm Reply
Joseph Schulman · 7 years ago

At least one of the authors of this piece is on the board of directors for this company. This is a conflict of interest and renders any conclusions reached in this study as suspect and of questionable objectivity.

December 22nd, 2011 | 2:23pm Reply

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